Endocrine Abstracts

Introduction: Neonatal hypoglycaemia (NH) is a well-recognized cause of adverse neurological outcomes. While hypoglycaemic brain injury is well reported in the literature there is limited data on the effect of neonatal hypoglycaemia solely with other risk factors for brain injury excluded. The aim of study was to evaluate the long-term outcome in patients with a history of symptomatic NH and no other risk factors of brain injury.Methodology: This retrosp...

Introduction: Short synacthan test is a first line endocrine test for diagnosing adrenal insufficiency except in situations like Pituitary surgery or Pituitary apoplexy within the last 2 weeks when this may give a false positive result and this is well known in literature. Here we discuss lesser reported clinical situations seen in two of our patients having good adrenal response to SST with only GST identifying adrenal insufficiency.Case Report: Two pat...

Introduction: Carbimazole is a first line antithyroid drug for thyrotoxicosis management in UK. Its main but rare complications include allergic reaction and risk of neutropenia. Here we discuss the lesser reported situation in which a thyrotoxic patient who is in a remission from Aplastic anaemia was treated with Carbimazole.Case Report: Out patient was seen in Ambulatory care with symptoms of heart failure along with tachycardia. Thyroid blood test sho...

Introduction: The commonest metastases to the thyroid are from renal cell carcinomas (RCC) and 23–48% of all thyroid metastases are RCCs. They may occur many years after RCC excision, the longest reported latent period being 20 years. Sunitinib (SUN), a multiple targeted anti-cancer drug, is increasingly used for RCC therapy but may cause thyroid dysfunction in some – usually hypothyroidism. We report a patient who presented with thyroid metastases 21 years after RCC...

Background: Adipose tissue dysfunction can play a role in the neuroendocrine and haematopoietic dysfunctions affecting thalassaemic patients.Aim of the work: In this work, we aimed to study the serum levels of adiponectin, an adipocytokine, in Egyptian β-thalassemia patients in relation to their endocrinal complications.Subjects and methods: The study included 60β-thalassaemia patients; (major, intermedia, and minor) and ...

Background: Vitamin D is a growing endemic problem. Wide proportions of healthy adults are deficient in vitamin D. It is very important for skeletal and non-skeletal health. It is now well established that many people have vitamin D levels that are less than currently recommended for optimal healthAim of this work: To assess vitamin-D sufficiency/deficiency in a sample of healthy Egyptian adult males in Dakahlia Governorate in Northern Egypt and correlat...

Introduction: Diabetes is often associated with complications and comorbidities. Osteoporosis (OP) is increasingly recognised as a significant comorbidity of type 2 diabetes mellitus (T2DM). The aim of this study was to determine the prevalence of OP in postmenopausal women with T2DM and to assess the association between T2DM and bone mineral density (BMD).Methods: This cross-sectional study was carried out in 50 postmenopausal women with type T2DM and 5...

Introduction: One tenth of children worldwide are obese and disturbance in pubertal progression is one of the unpleasant health consequences of adolescent obesity. Data on pubertal hormones in obese adolescents are scarce and contradictory.Methods: This study was a cross-sectional, case-control study conducted on 120 participants; 60 randomly chosen obese adolescent males and 60 age and sex matched controls. All participants had measurements of their wei...

Introduction: Intrathyroid metastases are rare (less than 1% of thyroid cancers). They can be synchronous or metachronous. The origin of primary cancer is variable; the kidney, lung, stomach and breast being the most described sites.Through this case, we describe the diagnostic difficulties that the pathologist may encounter in the identification of these metastases.Materials and methods: We report a case of intrathyroid metastasis...

Introduction: Cervical lymphadenopathy is a frequent reason for ENT consultation. In most cases the diagnosis is easy based on clinical, radiological and cytopathological data. However, in some situations, the diagnosis remains pending. The objective of this work is to study the possible difficulties face to a chronic cystic cervical lymphadenopathy.Materials and methods: It is a retrospective study bringing 4 cases of cervical cystic lymphadenopathy rev...